Luisi: The Emergence of Life: Autopoiesis: The Logic of Cellular Life

Luisi, P. L. (2006). The emergence of life : from chemical origins to synthetic biology. Cambridge: Cambridge University Press.

Chapter 8: Autopoiesis: The Logic of Cellular Life

Autopoiesis was coined by Varela and Maturana in the early 1970’s . It did not initially receive much attention, but slowly began to creep into scientific discourse. Probably most notably, it would used by Luhmann (1984) to describe social systems.

Initially, it was used as an analysis of cellular life. Cells are one of the basic building blocks of life on earth, and the simplest cells can be incredibly complex. On the outside of the cell lies the membrane, which is semi-permeable. “The notion of boundary is, in fact, one central concept in the theory of autopoiesis. Inside the boundary of a cell, many reactions and correspondingly many chemical transformations occur. However, despite all these chemical processes, the cell always maintains its own identity during its homeostasis period. This is because the cell…regenerates within its own boundary all those chemicals that are being destroyed or transformed…” (158). “The chain of processes occurring inside the boundary essentially serves the purpose of self-sustenance, or auto-maintenance. Of course, this takes pace at the expense of nutrients and energy coming from the medium. …the cell is a dissipative, open system” (158).

“An autopoietic unit is a system that is capable of sustaining itself due to an inner network of reaction that regenerate the system’s components” (158). A definition by Maturana: “When you regard a living system you always find a network of processes or molecules that interact in such a way as to produce the very network that produced them and that determine its boundary. Such a network I call autopoietic. Whenever you encounter a network whose operations eventually produce itself as a result, you are facing an autopoietic system. It produces itself. The system is open to the input of matter but closed with regard to the dynamics of the relations that generate it” (158).

Varela identifies three criterion for autopoietic systems: it must have a semi-permeable boundary, the boundary must have been produced by the system and that this boundary must encompass reactions, “that regenerate the components of the system” (159). This excludes viruses, for example, as being able to be defined as autopoietic, nor is a crystal.

There is then a discussion of autopoiesis and cognition/consciousness.

Social autopoiesis is then explored. “Consider, for example, a political party, or a family, whereby the rules that define a party o a family can be seen as a kind of boundary given by the social structure itself. The whole system enjoys a dynamic equilibrium, as certain members leave the structure, and new people come in, and are transformed into steady members by the binding rules of the party or of the family. There is a regeneration from within, there is the defense of the self-identity; the metaphor of the living cell applies. Also, in all these systems, certain characteristic features of biology can be recognized, such as the notion of emergence—the family being an emergent property arising from the organization of single individuals, etc” (175-6).